LIAVIUM-CA1 (pregabalin chewable tablets) is the first and only FDA conditionally approved pregabalin for the management of pain and clinical signs associated with Chiari-like malformation and syringomyelia in dogs
Pregabalin has long been the standard for managing neuropathic pain in humans. LIAVIUM-CA1 finally brings the proven science and relief to dogs.
Pregabalin dosed for dogs
30 mg
90 mg
180 mg
With a 6-7 hour elimination half life, LIAVIUM-CA1 is dosed only twice a day. This means there is less likelihood of breakthrough pain, and a potentially better therapeutic outcome.
Predictable
No compounding needed—FDA oversight ensures every dose meets quality standards.
Potent
High potency and rapid absorption work together to powerfully block pain signals.
Consistent
Twice-daily dosing maintains around-the-clock pain relief. No wearing off between doses—just steady comfort.
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ACVIM
6/11–6/13Seattle, WA
Booth 621
AVMA
7/10–7/14Anaheim, CA
Booth 1414
References
1Mayoral V, Galvez R, Ferrándiz M , Miguéns Vázquez X, Cordero-García C, Alcántara Montero A, Pérez C, Pérez-Páramo M. Pregabalin vs. gabapentin in the treatment of neuropathic pain: a comprehensive systematic review and meta-analysis of effectiveness and safety. Front Pain Res (Lausanne). 202 Jan 7;5:1513597.
2Dewey CW, Cerda-Gonzalez S, Levine JM, et al. Pregabalin as an adjunct to phenobarbital, potassium bromide, or a combination of phenobarbital and potassium bromide for treatment of dogs with suspected idiopathic epilepsy. J Am Vet Med Assoc . 2009 Dec 15;235(12): 1442-9.
3Bockbrader HN, Radulovic LL, Posvar EL, et al. Clinical pharmacokinetics of pregabalin in healthy volunteers. J Clin Pharmacol. 2010 Aug ;50(8): 941-50.
4Salazar V, Dewey C W, Schwark W, et al. Pharmacokinetics of single-dose oral pregabalin administration in normal dogs. Vet Anaesth Analg. 2009 Nov; 36(6):574-80.
